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Cat. No.: HY-159888

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SON38

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research.

For research use only. We do not sell to patients.

CAS No.: 3034673-37-2
Formula: C₂₁H₂₅ClN₄O₄
Molecular Weight:432.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

SON38 Chemical Structure

CAS No.: 3034673-37-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research^[1].

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
HepG2	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay	[PMID: 35462163]
SH-SY5Y	IC₅₀	>100 μM Compound: 12; SON38	Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 35462163]

Chemical Information

CAS No. 3034673-37-2
Molecular Weight 432.90
Formula C₂₁H₂₅ClN₄O₄
SMILES

ClC1=CC([N+]([O-])=O)=C(C=C1)OCC(NCCN2CCN(CC2)CC3=CC=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leuci R, et al. Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates[J]. Bioorganic Chemistry, 2024, 153: 107895. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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SON38

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SON38 Related Classifications

HY-159888 Related Classifications