1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. SON38

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research.

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SON38

SON38 Estructura química

No. CAS : 3034673-37-2

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Descripciòn

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
>100 μM
Compound: 12; SON38
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
[PMID: 35462163]
HepG2 IC50
>100 μM
Compound: 12; SON38
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 35462163]
SH-SY5Y IC50
>100 μM
Compound: 12; SON38
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
[PMID: 35462163]
SH-SY5Y IC50
>100 μM
Compound: 12; SON38
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 35462163]
Peso molecular

432.90

Fòrmula

C21H25ClN4O4

No. CAS
SMILES

ClC1=CC([N+]([O-])=O)=C(C=C1)OCC(NCCN2CCN(CC2)CC3=CC=CC=C3)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación
Referencias
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
SON38
Cat. No.:
HY-159888
Cantidad:
MCE Japan Authorized Agent: