21829-22-1
21829-22-1
Chemical Structure
Clonixeril
Synonym(s): NSC 335504
- CAS No.: 21829-22-1
- Formula:C16H17ClN2O4
- Molecular Weight:336.77
InChIKey: SWYJYGCPTGKBDS-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1NC2=C(C)C(Cl)=CC=C2)OCC(CO)O
Biological Activity: Clonixeril (NSC 335504) is a non-nucleotide hSTING modulator. Clonixeril has weak agonist activity at micromolar concentrations and results in antagonism of the hSTINGWT pathway at low femtomolar (10-15 M) and in some cases even attomolar (10-18 M) concentrations. Clonixeril reduces hSTING oligomerization at a concentration of 1 aM-1 pM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Clonixeril | 99.63% | Clonixeril (NSC 335504) is a non-nucleotide hSTING modulator. Clonixeril has weak agonist activity at micromolar concentrations and results in antagonism of the hSTINGWT pathway at low femtomolar (10-15 M) and in some cases even attomolar (10-18 M) concentrations. Clonixeril reduces hSTING oligomerization at a concentration of 1 aM-1 pM. | ||||||||||||||||||||
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References
Keywords
