218795-74-5
218795-74-5
Chemical Structure
IMM-01
- CAS. Nr.: 218795-74-5
- Formula:C12H17N3O2S
- Molecular Weight:267.35
IUPAC Name: (E)-N-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide
InChIKey: LTFUAYRGVLQXKC-NTUHNPAUSA-N
SMILES: OC1=CC=C(/C=N/NC(NC(C)(C)C)=S)C(O)=C1
Biological Activity: IMM-01 is a mammalian Diaphanous (mDia)-related formins agonist that inhibits DID-DAD (diaphanous inhibitory domain-diaphanous autoregulatory domain) binding with an IC50 of 140 nM. IMM-01 acts by disrupting the autoinhibitory bond between the DID and DAD domain and thus activates formins. IMM-01 shows anticancer effects[1].
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IMM-01 | 99.12% | IMM-01 is a mammalian Diaphanous (mDia)-related formins agonist that inhibits DID-DAD (diaphanous inhibitory domain-diaphanous autoregulatory domain) binding with an IC50 of 140 nM. IMM-01 acts by disrupting the autoinhibitory bond between the DID and DAD domain and thus activates formins. IMM-01 shows anticancer effects. | ||||||||||||||||||||
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