220751-00-8
Chemical Structure
Hypoglaunine D
- CAS No.: 220751-00-8
- Formula:C41H47NO19
- Molecular Weight:857.81
IUPAC Name: (52R,53R,54R,55S,55aR,56R,57R,58S,59S,59aS,510R)-55a-(((furan-3-carbonyl)oxy)methyl)-59-hydroxy-52,59,8,9-tetramethyl-2,7-dioxo-53,54,55,55a,56,57,58,59-octahydro-52H-3,6-dioxa-1(3,4)-pyridina-5(2,8)-3,9a-methanobenzo[b]oxepinacyclononaphane-54,55,56,57,5
InChIKey: YEUMGQWGGSDHAE-PWIKAHHMSA-N
SMILES: O=C(C1=COC=C1)OC[C@]23[C@@]45[C@@H]([C@]([C@H]([C@H]3OC(C)=O)OC(C)=O)([H])[C@@](O4)(COC(C6=CN=CC=C6C(C(C(O[C@]([C@@H]([C@@H]2OC(C)=O)OC(C)=O)([H])[C@@]5(O)C)=O)C)C)=O)C)OC(C)=O
Biological Activity: Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC50 value of 22 μg/ml[1].
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Hypoglaunine D | Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC50 value of 22 μg/ml. | |||||||||||||||||||||
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Keywords