2222768-84-3
Chemical Structure
Dynarrestin
- CAS No.: 2222768-84-3
- Formula:C22H23F2N3O2S
- Molecular Weight:431.50
IUPAC Name: ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate
InChIKey: UZNNDDDSGCMQOQ-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(N(CC)CC)C=C2)N=C(NC3=CC=C(F)C=C3F)S1)OCC
Biological Activity: Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dynarrestin | 98.18% | Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. | ||||||||||||||||||||
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