2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin inhibitor 49

Tubulin inhibitor 49 (Compound 18) is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell). Tubulin inhibitor 49 can be used in the research of cervical cancer.

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Tubulin inhibitor 49

Tubulin inhibitor 49 화학구조

CAS No. : 1023875-75-3

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Tubulin inhibitor 49 (Compound 18) is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell). Tubulin inhibitor 49 can be used in the research of cervical cancer[1].

분자량

377.38

화학식

C18H14F3N3OS
CAS No.
SMILES

O=C(C)NC1=CC=C(C2=CSC(NC3=CC=CC(C(F)(F)F)=C3)=N2)C=C1
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Keywords:

Tubulin inhibitor 491023875-75-3Tubulin inhibitor49Tubulin inhibitor-49Microtubule/TubulinHeLaHMF3aMDA-MB 231Inhibitorinhibitorinhibit

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Tubulin inhibitor 49
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HY-169882
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