2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin inhibitor 49 hydrobromide

Tubulin inhibitor 49 (Compound 18) hydrobromide is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 hydrobromide disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell). Tubulin inhibitor 49 hydrobromide can be used in the research of cervical cancer.

For research use only. We do not sell to patients.

Tubulin inhibitor 49 hydrobromide

Tubulin inhibitor 49 hydrobromide Chemical Structure

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Description

Tubulin inhibitor 49 (Compound 18) hydrobromide is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 hydrobromide disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell). Tubulin inhibitor 49 hydrobromide can be used in the research of cervical cancer[1].

Molecular Weight

458.30

Formula

C18H15BrF3N3OS
Appearance

Solid

Color

White to off-white

SMILES

O=C(C)NC1=CC=C(C2=CSC(NC3=CC=CC(C(F)(F)F)=C3)=N2)C=C1.Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Tubulin inhibitor 49 hydrobromide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin inhibitor 49Tubulin inhibitor49Tubulin inhibitor-49Microtubule/TubulinInhibitorinhibitorinhibit

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