2223027-70-9
Chemical Structure
VUF14738
- CAS No.: 2223027-70-9
- Formula:C25H32N4O2
- Molecular Weight:420.55
IUPAC Name: (E)-(3-((3-(3-(piperidin-1-yl)propoxy)phenyl)diazenyl)phenyl)(pyrrolidin-1-yl)methanone
InChIKey: AXFRZIJLVKELGM-CYYJNZCTSA-N
SMILES: O=C(C1=CC=CC(/N=N/C2=CC=CC(OCCCN3CCCCC3)=C2)=C1)N4CCCC4
Biological Activity: VUF14738 (compound 28) is a bidirectional photoswitch antagonist that can rapidly and reversibly photoisomerize at the histamine H3 receptor, with binding affinity increased or decreased upon illumination, and can be used in real-time electrophysiological experiments to study the activity of dynamic light modulation of receptor activation.
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VUF14738 | VUF14738 (compound 28) is a bidirectional photoswitch antagonist that can rapidly and reversibly photoisomerize at the histamine H3 receptor, with binding affinity increased or decreased upon illumination, and can be used in real-time electrophysiological experiments to study the activity of dynamic light modulation of receptor activation. | |||||||||||||||||||||
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Keywords