2226229-76-9
Chemical Structure
ATG7-IN-3
- CAS No.: 2226229-76-9
- Formula:C11H16N6O5S2
- Molecular Weight:376.41
IUPAC Name: ((2R,3S,5R)-5-(4-amino-3-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-3-hydroxytetrahydrofuran-2-yl)methyl sulfamate
InChIKey: PEIYQDSNKNROMJ-RRKCRQDMSA-N
SMILES: CSC1=NN([C@]2([H])O[C@@H]([C@H](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31
Biological Activity: ATG7-IN-3 (Compound 18) is a potent ATG7 inhibitor with an IC50 of 0.048 μM. ATG7-IN-3 inhibits Autophagy. ATG7-IN-3 inhibits the formation of LC3B puncta. ATG7-IN-3 can be used in the researches of glioma and colon cancer[1].
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ATG7-IN-3 | 98.17% | ATG7-IN-3 (Compound 18) is a potent ATG7 inhibitor with an IC50 of 0.048 μM. ATG7-IN-3 inhibits Autophagy. ATG7-IN-3 inhibits the formation of LC3B puncta. ATG7-IN-3 can be used in the researches of glioma and colon cancer. | ||||||||||||||||||||
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Keywords