2226229-76-9
2226229-76-9
Chemical Structure
ATG7-IN-3
- CAS. Nr.: 2226229-76-9
- Formula:C11H16N6O5S2
- Molecular Weight:376.41
IUPAC Name: ((2R,3S,5R)-5-(4-amino-3-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-3-hydroxytetrahydrofuran-2-yl)methyl sulfamate
InChIKey: PEIYQDSNKNROMJ-RRKCRQDMSA-N
SMILES: CSC1=NN([C@]2([H])O[C@@H]([C@H](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31
Biological Activity: ATG7-IN-3 (Compound 18) is a potent ATG7 inhibitor with an IC50 of 0.048 μM. ATG7-IN-3 inhibits Autophagy. ATG7-IN-3 inhibits the formation of LC3B puncta. ATG7-IN-3 can be used in the researches of glioma and colon cancer[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ATG7-IN-3 | 98.09% | ATG7-IN-3 (Compound 18) is a potent ATG7 inhibitor with an IC50 of 0.048 μM. ATG7-IN-3 inhibits Autophagy. ATG7-IN-3 inhibits the formation of LC3B puncta. ATG7-IN-3 can be used in the researches of glioma and colon cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.73
HY-145371ATG7-IN-1 -
Similarity Score 0.65
HY-146130ATG7-IN-2 -
Similarity Score 0.64
HY-161905ML471 -
Similarity Score 0.62
HY-171215ML901 -
Similarity Score 0.59
HY-182503GP515 -
Similarity Score 0.58
![6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Chemical Structure](//file.medchemexpress.com/product_pic/hy-154008.gif)
HY-1540086-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine -
Similarity Score 0.57
HY-1529962′-Deoxy-8-(methylthio)adenosine -
Similarity Score 0.57
HY-101136Dealanylascamycin -
Similarity Score 0.57
HY-1318125'-dAMPS -
Explore the MedChemAI to find more analogs
![6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-154008.gif)
