1. Autophagy
  2. Autophagy
  3. ATG7-IN-3

ATG7-IN-3 

Cat. No.: HY-146131
Handling Instructions

ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4.

For research use only. We do not sell to patients.

ATG7-IN-3 Chemical Structure

ATG7-IN-3 Chemical Structure

CAS No. : 2226229-76-9

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Description

ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].

IC50 & Target

IC50: 0.048 ± 0.022 μM (ATG7), 0.280 ± 0.051 μM (Thioester), 0.938 ± 0.231 μM (LC3B)[1]

Molecular Weight

376.41

Formula

C11H16N6O5S2

CAS No.
SMILES

CSC1=NN([[email protected]]2([H])O[[email protected]@H]([[email protected]](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ATG7-IN-3
Cat. No.:
HY-146131
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