2. Autophagy
  3. Atg8/LC3 Atg7 Autophagy
  4. ATG7-IN-3

ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4.

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ATG7-IN-3 Chemical Structure

ATG7-IN-3 Chemical Structure

CAS No. : 2226229-76-9

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ATG7-IN-3 Related Antibodies

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Description

ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].

IC50 & Target

IC50: 0.048 ± 0.022 μM (ATG7), 0.280 ± 0.051 μM (Thioester), 0.938 ± 0.231 μM (LC3B)[1]
Molecular Weight

376.41

Formula

C11H16N6O5S2
CAS No.
SMILES

CSC1=NN([C@]2([H])O[C@@H]([C@H](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ATG7-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATG7-IN-32226229-76-9Atg8/LC3Atg7AutophagyAutophagy-related 8| E1 enzymeautophagyH1650 cellsH4 cellsneurogliomaLC3BNBR1Inhibitorinhibitorinhibit

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