2227019-45-4
2227019-45-4
Chemical Structure
Aurora inhibitor 1
- CAS No.: 2227019-45-4
- Formula:C23H25N9S
- Molecular Weight:459.57
IUPAC Name: 3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
InChIKey: QTTGVGLTCILDCA-UHFFFAOYSA-N
SMILES: CC(N=C1NC2=CC(C(C3=CC=CC=N3)NC(C)(C)C)=NS2)=CN4C1=NC=C4C5=CNN=C5
Biological Activity: Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively[1].
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Aurora inhibitor 1 | Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively. | |||||||||||||||||||||
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References
Keywords
