223645-67-8
223645-67-8
Chemical Structure
Ripasudil free base
Synonym(s): K-115 free base
- CAS No.: 223645-67-8
- Formula:C15H18FN3O2S
- Molecular Weight:323.39
IUPAC Name: (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline
InChIKey: QSKQVZWVLOIIEV-NSHDSACASA-N
SMILES: FC1=CN=CC2=C1C(S(N3CCCNC[C@@H]3C)(=O)=O)=CC=C2
Biological Activity: Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
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Ripasudil free base | Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. | |||||||||||||||||||||
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Keywords
