2245231-10-9
Chemical Structure
Pirmitegravir
Synonym(s): STP0404
- CAS No.: 2245231-10-9
- Formula:C27H31ClN4O3
- Molecular Weight:495.01
IUPAC Name: (S)-2-(tert-butoxy)-2-(4-(4-chlorophenyl)-2,3,6-trimethyl-1-((1-methyl-1H-pyrazol-4-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)acetic acid
InChIKey: GNRDGAWRAIJOSU-DEOSSOPVSA-N
SMILES: O=C([C@H](C1=C(N=C(C2=C1C3=CC=C(C=C3)Cl)N(C(C)=C2C)CC4=CN(N=C4)C)C)OC(C)(C)C)O
Biological Activity: Pirmitegravir is a potent and first-in-class inhibitor of allosteric integrase (ALLINI) that targets LEDGF/p75 binding site. Pirmitegravir displays picomolar IC50 in human PBMCs with a >24,000 therapeutic index against HIV-1. Pirmitegravir harbors outstanding anti-virus and safety properties[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pirmitegravir | 99.79% | Pirmitegravir is a potent and first-in-class inhibitor of allosteric integrase (ALLINI) that targets LEDGF/p75 binding site. Pirmitegravir displays picomolar IC50 in human PBMCs with a >24,000 therapeutic index against HIV-1. Pirmitegravir harbors outstanding anti-virus and safety properties. | ||||||||||||||||||||
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Keywords
