2248124-46-9
2248124-46-9
Chemical Structure
HIV-1 protease-IN-2
- CAS No.: 2248124-46-9
- Formula:C27H34N4O7S
- Molecular Weight:558.65
IUPAC Name: 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-N-((2S,3R)-3-hydroxy-4-((N-isobutyl-4-methoxyphenyl)sulfonamido)-1-phenylbutan-2-yl)acetamide
InChIKey: YKVUCLKFVOEPGS-BJKOFHAPSA-N
SMILES: COC1=CC=C(C=C1)S(=O)(N(C[C@H]([C@@H](NC(CN2C=CC(NC2=O)=O)=O)CC3=CC=CC=C3)O)CC(C)C)=O
Biological Activity: HIV-1 protease-IN-2 is a potent HIV-1 protease inhibitor with an IC50 of 2.53 nM. HIV-1 protease-IN-2 shows antiviral activity against DRV (Darunavir)-sensitive or DRV-resistant HIV-1 variants[1].
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HIV-1 protease-IN-2 | HIV-1 protease-IN-2 is a potent HIV-1 protease inhibitor with an IC50 of 2.53 nM. HIV-1 protease-IN-2 shows antiviral activity against DRV (Darunavir)-sensitive or DRV-resistant HIV-1 variants. | |||||||||||||||||||||
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References
Keywords
