227619-64-9
Chemical Structure
(±)-HIP-A
- CAS No.: 227619-64-9
- Formula:C6H8N2O4
- Molecular Weight:172.14
IUPAC Name: (3aR,4S,6aR)-3-oxohexahydro-2H-pyrrolo[3,4-d]isoxazole-4-carboxylic acid
InChIKey: XJSXFNHFIBCTDU-HZLVTQRSSA-N
SMILES: OC([C@@H]1[C@]2([H])[C@](ONC2=O)([H])CN1)=O
Biological Activity: (±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].
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(±)-HIP-A | (±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases. | |||||||||||||||||||||
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Keywords