2289726-31-2
2289726-31-2
Chemical Structure
DCPT1061
- CAS No.: 2289726-31-2
- Formula:C17H20Cl2N2O
- Molecular Weight:339.26
InChIKey: GCURTAFSSBAXNO-UHFFFAOYSA-N
SMILES: ClC1=C(OC2=CC=CC=C2CN(C)CCNC)C=CC=C1Cl
Biological Activity: DCPT1061 potently inhibits PRMT1, PRMT6 and PRMT8 in vitro with less inhibitory effect on PRMT3, PRMT4, and PRMT5 or other epigenetic enzymes. DCPT1061 has antitumor effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DCPT1061 | 99.81% | DCPT1061 potently inhibits PRMT1, PRMT6 and PRMT8 in vitro with less inhibitory effect on PRMT3, PRMT4, and PRMT5 or other epigenetic enzymes. DCPT1061 has antitumor effect. | ||||||||||||||||||||
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References
- [1]. Jianfeng Wang, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 2021 Mar 12;11(11):5387-5403. [Content Brief]
- [2]. Hongru Tao, et al. PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma. Cancer Res. 2023 Nov 22. [Content Brief]
Keywords
