229030-20-0
Chemical Structure
Polyphemusin II-Derived Peptide
Synonym(s): T140
- CAS No.: 229030-20-0
- Formula:C90H141N33O18S2
- Molecular Weight:2037.42
InChIKey: IMOHHNXUCDZLKM-ADZSTZGASA-N
SMILES: O=C([C@@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)NC([C@H](CCCNC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC2=CC=C(O)C=C2)NC3=O)=O)=O)=O)NC([C@H](CC4=CC=C(C=CC=C5)C5=C4)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)CCCNC(N)=N)=O)=O)N6[C@@]3([H])CCC6
Biological Activity: Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4[1].
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Polyphemusin II-Derived Peptide | Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4. | |||||||||||||||||||||
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