23095-44-5
23095-44-5
Chemical Structure
Girinimbine
Synonym(s): Girinimbin
- CAS No.: 23095-44-5
- Formula:C18H17NO
- Molecular Weight:263.33
IUPAC Name: 3,3,5-trimethyl-3,11-dihydropyrano[3,2-a]carbazole
InChIKey: GAEQWKVGMHUUKO-UHFFFAOYSA-N
SMILES: CC(OC1=C(C)C=C23)(C)C=CC1=C3NC4=C2C=CC=C4
Biological Activity: Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities[1][2][3].
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Girinimbine | 99.23% | Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities. | ||||||||||||||||||||
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References
- [1]. Suvitha Syam, et al. The growth suppressing effects of girinimbine on HepG2 involve induction of apoptosis and cell cycle arrest. Molecules. 2011 Aug 23;16(8):7155-70. [Content Brief]
- [2]. Venoos Iman, et al. Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii. Drug Des Devel Ther. 2016 Dec 28;11:103-121. [Content Brief]
- [3]. H O Dyary, et al. Antitrypanosomal and cytotoxic activities of botanical extracts from Murraya koenigii (L.) and Alpinia mutica Roxb. Trop Biomed. 2019 Mar 1;36(1):94-102. [Content Brief]
Keywords
