2315311-83-0
2315311-83-0
Chemical Structure
GNE-9278
- CAS No.: 2315311-83-0
- Formula:C21H27N5O3S
- Molecular Weight:429.54
IUPAC Name: 4-cyclohexyl-N-(5-methyl-7-oxo-2-propyl-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide
InChIKey: OKXCVUICUUOADN-UHFFFAOYSA-N
SMILES: O=C1N(N=C2CCC)C(N2)=NC(C)=C1N[S](=O)(C3=CC=C(C4CCCCC4)C=C3)=O
Biological Activity: GNE-9278 is a highly selective positive allosteric modulator of NMDAR that acts at the GluN1 transmembrane domain (TMD). GNE-9278 acts on activated NMDARs to increase peak current and agonist affinity[1].
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GNE-9278 | 99.91% | GNE-9278 is a highly selective positive allosteric modulator of NMDAR that acts at the GluN1 transmembrane domain (TMD). GNE-9278 acts on activated NMDARs to increase peak current and agonist affinity. | ||||||||||||||||||||
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References
Keywords
