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PU.1-IN-1 (compound A11) is a potent PU.1 inhibitor with an IC50 of 2 nM. PU.1-IN-1 has anti-inflammatory properties.

For research use only. We do not sell to patients.

PU.1-IN-1 Chemical Structure

PU.1-IN-1 Chemical Structure

CAS No. : 873588-27-3

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5 mg USD 32 In-stock
10 mg USD 50 In-stock
25 mg USD 95 In-stock
50 mg USD 150 In-stock
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Based on 1 publication(s) in Google Scholar

PU.1-IN-1 Related Antibodies

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Description

PU.1-IN-1 (compound A11) is a potent PU.1 inhibitor with an IC50 of 2 nM. PU.1-IN-1 has anti-inflammatory properties[1].

Molecular Weight

330.44

Formula

C18H22N2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(C2CCCCC2)C=C1)(NCC3=CC=NC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (378.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0263 mL 15.1313 mL 30.2627 mL
5 mM 0.6053 mL 3.0263 mL 6.0525 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0263 mL 15.1313 mL 30.2627 mL 75.6567 mL
5 mM 0.6053 mL 3.0263 mL 6.0525 mL 15.1313 mL
10 mM 0.3026 mL 1.5131 mL 3.0263 mL 7.5657 mL
15 mM 0.2018 mL 1.0088 mL 2.0175 mL 5.0438 mL
20 mM 0.1513 mL 0.7566 mL 1.5131 mL 3.7828 mL
25 mM 0.1211 mL 0.6053 mL 1.2105 mL 3.0263 mL
30 mM 0.1009 mL 0.5044 mL 1.0088 mL 2.5219 mL
40 mM 0.0757 mL 0.3783 mL 0.7566 mL 1.8914 mL
50 mM 0.0605 mL 0.3026 mL 0.6053 mL 1.5131 mL
60 mM 0.0504 mL 0.2522 mL 0.5044 mL 1.2609 mL
80 mM 0.0378 mL 0.1891 mL 0.3783 mL 0.9457 mL
100 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.7566 mL
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PU.1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PU.1-IN-1873588-27-3OthersInhibitorinhibitorinhibit

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