2367619-63-2
2367619-63-2
Chemical Structure
TMX-4100
- CAS No.: 2367619-63-2
- Formula:C11H10N4O2S
- Molecular Weight:262.29
IUPAC Name: 3-(4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl)piperidine-2,6-dione
InChIKey: PGEUBQZQGXWTFO-UHFFFAOYSA-N
SMILES: O=C(C(N1N=NC(C2=CSC=C2)=C1)CC3)NC3=O
Biological Activity: TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. TMX-4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4100 can be used for the research of multiple myeloma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TMX-4100 | 98.26% | TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. TMX-4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4100 can be used for the research of multiple myeloma. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.78
HY-145320TMX-4113 -
Similarity Score 0.78
HY-145319FPFT-2216 -
Similarity Score 0.59
HY-W999669Hydrouracil-4-benzazimide-7-NH2 -
Similarity Score 0.59
HY-W998243CRBN ligand-612 -
Similarity Score 0.58
HY-114406TD-106 -
Similarity Score 0.57
HY-W1003189E3 ligase Ligand 42 -
Similarity Score 0.55
HY-163927E3 ligase Ligand 29 -
Similarity Score 0.55
HY-W999562CRBN ligand-706 -
Similarity Score 0.55
HY-150766KPC-2-IN-1 -
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