2375595-72-3
2375595-72-3
Chemical Structure
HPK1-IN-2 dihydrochloride
- CAS No.: 2375595-72-3
- Formula:C19H22Cl2N6OS
- Molecular Weight:453.39
IUPAC Name: 4-amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride
InChIKey: XESGZTINOLHKPH-UHFFFAOYSA-N
SMILES: O=C1C(C2=NC3=CC=C(N4CCN(C)CC4)C=C3N2)=C(N)C(C=CS5)=C5N1.[H]Cl.[H]Cl
Biological Activity: HPK1-IN-2 dihydrochloride is an orally active HPK1 inhibitor (IC50 < 0.05 µM) with antitumor activity. HPK1-IN-2 dihydrochloride inhibits the activity of Lck (IC50 < 0.05 µM) and Flt3 (IC50 < 0.05 µM) kinases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HPK1-IN-2 dihydrochloride | 98.03% | HPK1-IN-2 dihydrochloride is an orally active HPK1 inhibitor (IC50 < 0.05 µM) with antitumor activity. HPK1-IN-2 dihydrochloride inhibits the activity of Lck (IC50 < 0.05 µM) and Flt3 (IC50 < 0.05 µM) kinases. | ||||||||||||||||||||
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