2407451-82-3
2407451-82-3
Chemical Structure
ASK1-IN-6
- CAS No.: 2407451-82-3
- Formula:C17H14F4N6O2
- Molecular Weight:410.33
InChIKey: MXOCTLMVBIGSKH-VIFPVBQESA-N
SMILES: FC(F)(F)[C@@H](N1C(C2=CC=CC(NC(C3=C(N=CC(F)=C3)OC)=O)=N2)=NN=C1)C
Biological Activity: ASK1-IN-6 is a selective, orally active, and blood-brain barrier penetrant inhibitor of ASK1 (biochemical IC50: 7 nM; cellular IC50: 25 nM). ASK1-IN-6 exhibits anti-inflammatory and can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASK1-IN-6 | 99.66% | ASK1-IN-6 is a selective, orally active, and blood-brain barrier penetrant inhibitor of ASK1 (biochemical IC50: 7 nM; cellular IC50: 25 nM). ASK1-IN-6 exhibits anti-inflammatory and can be used in the research of neurodegenerative diseases such as Alzheimer's disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-163752CS17919 -
Similarity Score 0.63
HY-174860ASK1 ligand 1 -
Similarity Score 0.60
HY-133554ASK1-IN-1 -
Similarity Score 0.58
HY-131969ASK1-IN-2 -
Similarity Score 0.55
HY-161283JT21-25 -
Similarity Score 0.55
HY-18938Selonsertib -
Similarity Score 0.55
HY-18938ASelonsertib hydrochloride -
Similarity Score 0.53
HY-153448HPK1-IN-36 -
Similarity Score 0.53
HY-146729ASK1-IN-3 -
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