2408065-32-5

PLN-1474 Chemical Structure
2408065-32-5

Chemical Structure

PLN-1474

  • CAS No.: 2408065-32-5
  • Formula:C24H37N3O4
  • Molecular Weight:431.57

IUPAC Name: (S)-2-(4-methyltetrahydro-2H-pyran-4-carboxamido)-9-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid

InChIKey: GELVLHVQVRSFAY-FQEVSTJZSA-N

SMILES: O=C(O)[C@H](CCCCCCCC1=CC=C2C(N1)=NCCC2)NC(C3(C)CCOCC3)=O

Biological Activity: PLN-1474 (compound 1) is an orally active and selective ανβ1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.

Cat. No. Product Name Purity Description Pricing
HY-47888 		PLN-1474 99.64% PLN-1474 (compound 1) is an orally active and selective ανβ1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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