2408286-73-5
2408286-73-5
Chemical Structure
HDAC6-IN-10
- CAS No.: 2408286-73-5
- Formula:C21H20N4O4
- Molecular Weight:392.41
IUPAC Name: (R)-4-((3-((1H-indol-3-yl)methyl)-2,5-dioxopiperazin-1-yl)methyl)-N-hydroxybenzamide
InChIKey: OUWQFNHQQZCXTJ-GOSISDBHSA-N
SMILES: O=C(NO)C1=CC=C(CN2C([C@@H](CC3=CNC4=C3C=CC=C4)NC(C2)=O)=O)C=C1
Biological Activity: HDAC6-IN-10 is a highly selective HDAC6 inhibitor with the IC50 of 0.73 nM. HDAC6-IN-10 has 144~10941-fold selectivity over other HDAC isoforms. HDAC6-IN-10 shows anti-proliferative activities against multiple myeloma cells[1].
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HDAC6-IN-10 | HDAC6-IN-10 is a highly selective HDAC6 inhibitor with the IC50 of 0.73 nM. HDAC6-IN-10 has 144~10941-fold selectivity over other HDAC isoforms. HDAC6-IN-10 shows anti-proliferative activities against multiple myeloma cells. | |||||||||||||||||||||
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References
Keywords
