2410846-16-9
Chemical Structure
SIC5-6
- CAS No.: 2410846-16-9
- Formula:C27H24IN3O2S
- Molecular Weight:581.47
IUPAC Name: 3,3'-(1-((4-iodophenyl)sulfonyl)piperidine-4,4-diyl)bis(1H-indole)
InChIKey: JRVKJWXBSOQUOI-UHFFFAOYSA-N
SMILES: O=[S](N1CCC(C2=CNC3=CC=CC=C23)(C4=CNC5=CC=CC=C45)CC1)(C(C=C6)=CC=C6I)=O
Biological Activity: SIC5-6 is a potent Separase inhibitor. Separase, a large cysteine protease, involves in chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, spindle stabilization and elongation. Separase is highly overexpressed in many solid cancers, serves as an attractive chemotherapeutic target[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SIC5-6 | 99.83% | SIC5-6 is a potent Separase inhibitor. Separase, a large cysteine protease, involves in chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, spindle stabilization and elongation. Separase is highly overexpressed in many solid cancers, serves as an attractive chemotherapeutic target. | ||||||||||||||||||||
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Keywords
