2410846-16-9
Chemical Structure
SIC5-6
- CAS. Nr.: 2410846-16-9
- Formula:C27H24IN3O2S
- Molecular Weight:581.47
IUPAC Name: 3,3'-(1-((4-iodophenyl)sulfonyl)piperidine-4,4-diyl)bis(1H-indole)
InChIKey: JRVKJWXBSOQUOI-UHFFFAOYSA-N
SMILES: O=[S](N1CCC(C2=CNC3=CC=CC=C23)(C4=CNC5=CC=CC=C45)CC1)(C(C=C6)=CC=C6I)=O
Biological Activity: SIC5-6 is a potent Separase inhibitor. Separase, a large cysteine protease, involves in chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, spindle stabilization and elongation. Separase is highly overexpressed in many solid cancers, serves as an attractive chemotherapeutic target[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SIC5-6 | 99.83% | SIC5-6 is a potent Separase inhibitor. Separase, a large cysteine protease, involves in chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, spindle stabilization and elongation. Separase is highly overexpressed in many solid cancers, serves as an attractive chemotherapeutic target. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.53
HY-N192261,1,3-Tris(3-indolyl)butane -
Similarity Score 0.52
HY-19808C-DIM12 -
Similarity Score 0.52
HY-112055DIM-C-pPhOH -
Similarity Score 0.52
HY-169581DIM-C-pPhtBu -
Similarity Score 0.52
HY-111492DIM-C-pPhOCH3 -
Similarity Score 0.50
HY-145873BI-10 -
Similarity Score 0.50
HY-179528DIM-3,5-Cl2 -
Similarity Score 0.49
HY-161991Caspase-3 activator 4 -
Similarity Score 0.49
HY-N101172,3-Bis(3-indolylmethyl)indole -
Explore the MedChemAI to find more analogs
