2417307-52-7
2417307-52-7
Chemical Structure
α4β7 Integrin-IN-1
- CAS No.: 2417307-52-7
- Formula:C33H28F4N6O6
- Molecular Weight:680.61
InChIKey: WEIBBGLWYPNZOH-JYFHCDHNSA-N
SMILES: CN(C(N1C2=CC=C(C3=C2N=CC=C3)C[C@H](NC(C(C(F)=C4)=C(C)C=C4N5CCOC[C@@H]5C(F)(F)F)=O)C(O)=O)=O)C6=CN=CC=C6C1=O
Biological Activity: α4β7 Integrin-IN-1 (Example 356) is a potent inhibitor of α4β7 integrin (integrin). Its ability to block the interaction between α4β7 integrin and MadCAM-1 (EC50) is 0.05 nM. α4β7 Integrin-IN-1 can be used for the study of inflammatory bowel disease[1].
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α4β7 Integrin-IN-1 | α4β7 Integrin-IN-1 (Example 356) is a potent inhibitor of α4β7 integrin (integrin). Its ability to block the interaction between α4β7 integrin and MadCAM-1 (EC50) is 0.05 nM. α4β7 Integrin-IN-1 can be used for the study of inflammatory bowel disease. | |||||||||||||||||||||
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References
Keywords
