2426547-83-1
2426547-83-1
Chemical Structure
HYL001
- CAS No.: 2426547-83-1
- Formula:C21H18N4O
- Molecular Weight:342.39
InChIKey: STJSBQUPJDTPOW-UHFFFAOYSA-N
SMILES: OC1=CC2=C(C3=C(CCC4)N4N=C3C5=CC=CC(C)=N5)C=CN=C2C=C1
Biological Activity: HYL001 (compund 338) is a potent inhibitor of TGFβ receptor 1 (ALK5) that is approximately 9 times more potent than the structurally related compound Galunisertib (HY-13226) and is able to eliminate liver metastases established in mice[1].
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HYL001 | 99.94% | HYL001 (compund 338) is a potent inhibitor of TGFβ receptor 1 (ALK5) that is approximately 9 times more potent than the structurally related compound Galunisertib (HY-13226) and is able to eliminate liver metastases established in mice. | ||||||||||||||||||||
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