2. TGF-beta/Smad
  3. TGF-β Receptor
  4. Galunisertib monohydrate

Galunisertib monohydrate is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 of 56 nM.

For research use only. We do not sell to patients.

CAS No. : 924898-09-9

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Galunisertib monohydrate Related Antibodies

Top Publications Citing Use of Products

68 Publications Citing Use of MCE Galunisertib monohydrate

Flow Cytometry
In Vivo Imaging
RT-PCR
IF
Cell Imaging/Staining

    Galunisertib monohydrate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 7;10(1):332.  [Abstract]

    LY2157299 (100 mg/kg; oral gavage). The frequencies of CD31+VE-Cadherin+ECs within CD45-Ter119- BM cells from mice subjected to the specified treatments were assessed through flow cytometry.

    Galunisertib monohydrate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 7;10(1):332.  [Abstract]

    LY2157299 (100 μM; 24 h). The mRNA level of PTN in BM ECs treated with TGF-β1 alone or in combination with LY2157299 (LY) was assessed via qPCR.

    Galunisertib monohydrate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 7;10(1):332.  [Abstract]

    LY2157299 (100 μM; 24 h). Representative images of double-positive BM ECs (yellow) co-stained with DiI-AcLDL (red) and FITC-UEA I (green) following the indicated treatments.

    Galunisertib monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2023 Oct 3;42(1):258.  [Abstract]

    Galunisertib (75 mg/kg; oral gavage). Representative bioluminescent images and BLI analysis of mice with intrasplenic injection of MKN45 cells showed the inhibitory effect of the anti-LBP antibody and galunisertib on LM in vivo.

    Galunisertib monohydrate purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2023 Oct 3;42(1):258.  [Abstract]

    Galunisertib (75 mg/kg; oral gavage). IF was applied to confirm that galunisertib inhibit the actin remodeling of MKN45 cells.

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    Galunisertib monohydrate Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Galunisertib924898-09-9TGF-β ReceptorTransforming growth factor beta receptorsInhibitorinhibitorinhibit

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