2464465-06-1
Chemical Structure
HDAC8-IN-16
- CAS No.: 2464465-06-1
- Formula:C21H24N4O3
- Molecular Weight:380.44
InChIKey: SYJFPDFQPQBVDR-SFHVURJKSA-N
SMILES: O=C(N1CCC(CC1)[C@H](CO)O)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4
Biological Activity: HDAC8-IN-16 is a selective histone deacetylase 8 (HDAC8) inhibitor with an IC50 of 0.16 μM. HDAC8-IN-16 induces cell apoptosis, triggers G2/M phase cell cycle arrest, and moderately inhibits cancer cell proliferation. HDAC8-IN-16 is applicable to relevant research on colorectal cancer[1].
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HDAC8-IN-16 | HDAC8-IN-16 is a selective histone deacetylase 8 (HDAC8) inhibitor with an IC50 of 0.16 μM. HDAC8-IN-16 induces cell apoptosis, triggers G2/M phase cell cycle arrest, and moderately inhibits cancer cell proliferation. HDAC8-IN-16 is applicable to relevant research on colorectal cancer. | |||||||||||||||||||||
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Keywords