246872-58-2
Chemical Structure
BAY38-7690
- CAS 番号: 246872-58-2
- Formula:C19H16ClF2N3O2
- Molecular Weight:391.80
IUPAC Name: ethyl (R)-6-(2-chloro-4-fluorophenyl)-2-(3-fluoropyridin-2-yl)-4-methyl-1,6-dihydropyrimidine-5-carboxylate
InChIKey: KUNKHBQPUQEYFO-INIZCTEOSA-N
SMILES: CCOC(C1=C(C)N=C(C2=C(C=CC=N2)F)N[C@H]1C3=C(C=C(C=C3)F)Cl)=O
Biological Activity: BAY38-7690 is a non-nucleoside inhibitor that inhibits HBV replication. BAY38-7690 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY38-7690 against HBV in stably transfected HepG2.2.15 cells is 0.15 μM[1].
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BAY38-7690 | BAY38-7690 is a non-nucleoside inhibitor that inhibits HBV replication. BAY38-7690 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY38-7690 against HBV in stably transfected HepG2.2.15 cells is 0.15 μM. | |||||||||||||||||||||
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Keywords
