2480283-75-6
2480283-75-6
Chemical Structure
hCAI/II-IN-2
- CAS No.: 2480283-75-6
- Formula:C12H12N4O5S2
- Molecular Weight:356.38
IUPAC Name: ethyl 5-(4-sulfamoylbenzamido)-1,3,4-thiadiazole-2-carboxylate
InChIKey: HRSGBOLVGNUHSW-UHFFFAOYSA-N
SMILES: O=C(C1=NN=C(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)S1)OCC
Biological Activity: hCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1].
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hCAI/II-IN-2 | hCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity. | |||||||||||||||||||||
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References
Keywords
