2499713-65-2

TbPTR1 inhibitor 1 Chemical Structure
2499713-65-2

Chemical Structure

TbPTR1 inhibitor 1

  • CAS No.: 2499713-65-2
  • Formula:C22H21N7O
  • Molecular Weight:399.45

IUPAC Name: (4-(((2,4-diaminopteridin-6-yl)methyl)(ethyl)amino)phenyl)(phenyl)methanone

InChIKey: ASBJYAZYFSRQAB-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C(N(CC)CC2=CN=C(N=C(N)N=C3N)C3=N2)C=C1)C4=CC=CC=C4

Biological Activity: TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM)[1].

Cat. No. Product Name Purity Description Pricing
HY-147940 		TbPTR1 inhibitor 1 TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM).
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