2499962-58-0
2499962-58-0
Chemical Structure
MTK458
Synonym(s): EP-0035985
- CAS No.: 2499962-58-0
- Formula:C17H15F3N4
- Molecular Weight:332.32
IUPAC Name: (R)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-6-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
InChIKey: JOIONRWKOGDQOG-CYBMUJFWSA-N
SMILES: FC(F)(F)C1=CC(C(N1)=NC=N2)=C2N[C@H]3C4=CC=CC=C4CCC3
Biological Activity: MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MTK458 | 99.45% | MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease. | ||||||||||||||||||||
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References
Keywords
