2511248-11-4

JNJ-74856665 Chemical Structure
2511248-11-4

Chemical Structure

JNJ-74856665

Synonym(s): DHODH-IN-16

  • CAS No.: 2511248-11-4
  • Formula:C24H25FN4O3
  • Molecular Weight:436.48

IUPAC Name: 6-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one

InChIKey: BZKHQYHQHLKJNX-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2

Biological Activity: JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].

Cat. No. Product Name Purity Description Pricing
HY-139189
JNJ-74856665 99.74% JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH.
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