2511248-11-4
2511248-11-4
Chemical Structure
JNJ-74856665
Synonym(s): DHODH-IN-16; JNJ-6665
- CAS. Nr.: 2511248-11-4
- Formula:C24H25FN4O3
- Molecular Weight:436.48
IUPAC Name: 6-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one
InChIKey: BZKHQYHQHLKJNX-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2
Biological Activity: JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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JNJ-74856665 | 99.74% | JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-112645BAY-2402234 -
Similarity Score 0.52
HY-144169DHODH-IN-19 -
Similarity Score 0.48
HY-139889DHODH-IN-18 -
Similarity Score 0.46
HY-181033(M)-AVI-4773 -
Similarity Score 0.45
HY-124487GK-136901 -
Similarity Score 0.45
HY-173337HSP90α-IN-1 -
Similarity Score 0.45
HY-171261CID15997213 -
Similarity Score 0.45
HY-10110RIC-87114 (Standard) -
Similarity Score 0.45
HY-129314CM-39 -
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