1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Dihydroorotate Dehydrogenase DNA/RNA Synthesis
  3. DHODH-IN-19

DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1).

For research use only. We do not sell to patients.

DHODH-IN-19 Chemical Structure

DHODH-IN-19 Chemical Structure

CAS No. : 2742675-85-8

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Description

DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1)[1].

Molecular Weight

521.84

Formula

C22H18ClF6N3O3

CAS No.
SMILES

O=C1N(C2=CC(O[C@@H](C)C(F)(F)F)=C(C=C2F)/C(F)=C/C3=C(C=CC=C3F)Cl)N=C(N1CC)CO

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DHODH-IN-19
Cat. No.:
HY-144169
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