2522920-65-4
2522920-65-4
Chemical Structure
Naa50-IN-1
- CAS No.: 2522920-65-4
- Formula:C23H24N10O5S
- Molecular Weight:552.57
InChIKey: SYFLGRBSBZONAM-DZKIICNBSA-N
SMILES: O=C(C1=CC=C(C2=NN=NN2)C=C1)N3[C@H](C4=NC(C(NC)=O)=CS4)C[C@@H](C3)NC([C@@H]5CC(N(C(N5)=O)C)=O)=O
Biological Activity: Naa50-IN-1 is an N-alpha-acetyltransferase 50 (Naa50) inhibitor with an IC50 of 7 nM against the human protein. Naa50-IN-1 exhibits selectivity toward the related enzymes Naa10 and Naa60. Naa50-IN-1 binds to the substrate-binding pocket of Naa50, and its binding affinity is enhanced by AcCoA[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naa50-IN-1 | 99.76% | Naa50-IN-1 is an N-alpha-acetyltransferase 50 (Naa50) inhibitor with an IC50 of 7 nM against the human protein. Naa50-IN-1 exhibits selectivity toward the related enzymes Naa10 and Naa60. Naa50-IN-1 binds to the substrate-binding pocket of Naa50, and its binding affinity is enhanced by AcCoA. | ||||||||||||||||||||
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References
Keywords
