2541792-70-3
2541792-70-3
Chemical Structure
ASK1-IN-2
- CAS No.: 2541792-70-3
- Formula:C19H17FN6O
- Molecular Weight:364.38
IUPAC Name: 6-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-1H-indole-2-carboxamide
InChIKey: LYUQNMNUBOUCBX-UHFFFAOYSA-N
SMILES: O=C(C(N1)=CC2=C1C=C(F)C=C2)NC3=NC(C4=NN=CN4C(C)C)=CC=C3
Biological Activity: ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASK1-IN-2 | 99.37% | ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-161283JT21-25 -
Similarity Score 0.67
HY-174860ASK1 ligand 1 -
Similarity Score 0.59
HY-18938Selonsertib -
Similarity Score 0.59
HY-18938ASelonsertib hydrochloride -
Similarity Score 0.58
HY-160939ASK1-IN-6 -
Similarity Score 0.57
HY-133554ASK1-IN-1 -
Similarity Score 0.56
HY-146729ASK1-IN-3 -
Similarity Score 0.55
HY-163752CS17919 -
Similarity Score 0.51
HY-176880ASK1-IN-9 -
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