2565705-01-1
2565705-01-1
Chemical Structure
Dot1L-IN-6
- CAS No.: 2565705-01-1
- Formula:C25H21ClF2N6O6S
- Molecular Weight:606.99
IUPAC Name: (S)-N1-((3-chloropyridin-2-yl)(2,2-difluorobenzo[d][1,3]dioxol-4-yl)methyl)-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)benzene-1,2-diamine
InChIKey: ZKUCSIBYPOHTCH-IBGZPJMESA-N
SMILES: O=S(C1=CC=C(N[C@H](C2=NC=CC=C2Cl)C3=C4OC(F)(F)OC4=CC=C3)C(NC5=NC(OC)=NC(OC)=N5)=C1)(C)=O
Biological Activity: Dot1L-IN-6 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.19 nM[1].
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Dot1L-IN-6 | Dot1L-IN-6 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.19 nM. | |||||||||||||||||||||
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