25967-29-7
25967-29-7
Chemical Structure
Flutoprazepam
Synonym(s): KB-509
- CAS No.: 25967-29-7
- Formula:C19H16ClFN2O
- Molecular Weight:342.79
IUPAC Name: 7-chloro-1-(cyclopropylmethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
InChIKey: OFVXPDXXVSGEPX-UHFFFAOYSA-N
SMILES: O=C1N(CC2CC2)C3=C(C(C4=C(F)C=CC=C4)=NC1)C=C(Cl)C=C3
Biological Activity: Flutoprazepam (KB-509), a benzodiazepine drug, possesses anticonflict effect. Flutoprazepam (KB-509) prevents maximal electroshock, pentetrazol, and strychnine-induced convulsions in mice[1][2].
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Flutoprazepam | Flutoprazepam (KB-509), a benzodiazepine drug, possesses anticonflict effect. Flutoprazepam (KB-509) prevents maximal electroshock, pentetrazol, and strychnine-induced convulsions in mice. | |||||||||||||||||||||
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References
- [1]. N Barzaghi, et al. Pharmacokinetics of flutoprazepam, a novel benzodiazepine drug, in normal subjects. Eur J Drug Metab Pharmacokinet. 1989 Oct-Dec;14(4):293-8. [Content Brief]
- [2]. S Ueki, Behavioral effects of flutoprazepam (KB-509) and its metabolites. Nihon Yakurigaku Zasshi. 1982 Jul;80(1):15-30. [Content Brief]
