2641601-67-2
2641601-67-2
Chemical Structure
PROTAC EZH2 Degrader-1
- CAS No.: 2641601-67-2
- Formula:C54H67N7O8
- Molecular Weight:942.15
IUPAC Name: (2R,4S)-2-amino-5,5,5-trifluoro-4-methylpentanoic acid
InChIKey: LONVYJSHGSZBQY-UHFFFAOYSA-N
SMILES: CCN(C1CCOCC1)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(C4=CC=C(C=C4)CN5CCN(CC5)CCCCCCCOC6=C7C(N(C(C7=CC=C6)=O)C8CCC(NC8=O)=O)=O)=C2)C
Biological Activity: PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PROTAC EZH2 Degrader-1 | 99.44% | PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-181391PROTAC EZH2 Degrader-34 -
Similarity Score 0.99
HY-181331PROTAC EZH2 Degrader-27 -
Similarity Score 0.98
HY-181354PROTAC EZH2 Degrader-36 -
Similarity Score 0.97
HY-181327PROTAC EZH2 Degrader-26 -
Similarity Score 0.97
HY-181332PROTAC EZH2 Degrader-37 -
Similarity Score 0.96
HY-181333PROTAC EZH2 Degrader-38 -
Similarity Score 0.96
HY-181326PROTAC EZH2 Degrader-25 -
Similarity Score 0.95
HY-181334PROTAC EZH2 Degrader-39 -
Similarity Score 0.77
HY-168131PROTAC EZH2 Degrader-3 -
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