2683-90-1
2683-90-1
Chemical Structure
8-Azahypoxanthine
- CAS No.: 2683-90-1
- Formula:C4H3N5O
- Molecular Weight:137.10
IUPAC Name: 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
InChIKey: OEEYCNOOAHGFHL-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CN1)NN=N2
Biological Activity: 8-Azahypoxanthine is a purine analog and an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT). 8-Azahypoxanthine exhibits antitumor activity and can be used in the research of tumors such as adenocarcinoma[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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8-Azahypoxanthine | 98.99% | 8-Azahypoxanthine is a purine analog and an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT). 8-Azahypoxanthine exhibits antitumor activity and can be used in the research of tumors such as adenocarcinoma. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-N0091RHypoxanthine (Standard) -
Similarity Score 0.83
HY-B0219RAllopurinol (Standard) -
Similarity Score 0.82
HY-B0219AAllopurinol sodium -
Similarity Score 0.82
HY-B1468R8-Azaguanine (Standard) -
Similarity Score 0.81
HY-W777809Guanine-13C2,15N -
Similarity Score 0.81
HY-W778114Guanine-13C2,7-15N -
Similarity Score 0.81
HY-Y1055S3Guanine-15N5 -
Similarity Score 0.78
HY-N0091SHypoxanthine-13C5,15N4 -
Similarity Score 0.78
HY-N0091S3Hypoxanthine-13C2,15N -
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References
- [1]. M H Vaughan, et al. Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro. Exp Cell Res. 1971, 69, 1. [Content Brief]
- [2]. Bennett LL Jr, et al. Studies with 8-azainosine, a cytotoxic nucleoside with antitumor activity. Cancer Res. 1973 Mar;33(3):465-71. [Content Brief]
