2683-90-1
2683-90-1
Chemical Structure
8-Azahypoxanthine
- CAS No.: 2683-90-1
- Formula:C4H3N5O
- Molecular Weight:137.10
IUPAC Name: 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
InChIKey: OEEYCNOOAHGFHL-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CN1)NN=N2
Biological Activity: 8-Azahypoxanthine is a purine analog and an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT). 8-Azahypoxanthine exhibits antitumor activity and can be used in the research of tumors such as adenocarcinoma[1][2].
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8-Azahypoxanthine | 98.99% | 8-Azahypoxanthine is a purine analog and an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT). 8-Azahypoxanthine exhibits antitumor activity and can be used in the research of tumors such as adenocarcinoma. | ||||||||||||||||||||
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References
- [1]. M H Vaughan, et al. Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro. Exp Cell Res. 1971, 69, 1. [Content Brief]
- [2]. Bennett LL Jr, et al. Studies with 8-azainosine, a cytotoxic nucleoside with antitumor activity. Cancer Res. 1973 Mar;33(3):465-71. [Content Brief]
Keywords
