2688098-11-3
2688098-11-3
Chemical Structure
CDK4/6-IN-10
- CAS No.: 2688098-11-3
- Formula:C22H23FN8
- Molecular Weight:418.47
IUPAC Name: 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
InChIKey: DIRJXVHFPSKLII-UHFFFAOYSA-N
SMILES: CN1C=C(C2=NC(NC3=NC=C(CN4CCNCC4)C=C3)=NC=C2F)C5=CC=CN=C51
Biological Activity: CDK4/6-IN-10 is a potent, selective and orally active CDK4 and CDK6 inhibitor with IC50s of 22 nM and 10 nM, respectively. CDK4/6-IN-10 shows antitumor activity. CDK4/6-IN-10 has the potential for the research of Multiple myeloma (MM)[1].
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CDK4/6-IN-10 | CDK4/6-IN-10 is a potent, selective and orally active CDK4 and CDK6 inhibitor with IC50s of 22 nM and 10 nM, respectively. CDK4/6-IN-10 shows antitumor activity. CDK4/6-IN-10 has the potential for the research of Multiple myeloma (MM). | |||||||||||||||||||||
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References
Keywords
