2714432-83-2
2714432-83-2
Chemical Structure
YAP-TEAD-IN-2
- CAS No.: 2714432-83-2
- Formula:C25H24ClFN2O4
- Molecular Weight:470.92
IUPAC Name: methyl 2-(2-azaspiro[3.3]heptan-6-yl)acetate hydrochloride
InChIKey: DMOHFURXRRTVGP-RUZDIDTESA-N
SMILES: NC[C@]1(CC2=[C@@](C(Cl)=CC=C2O1)[C@@]3=C(C(N)=O)C=CC(OCCOC)=C3F)C4=CC=CC=C4
Biological Activity: YAP-TEAD-IN-2 (compound 6) is a potent YAP-TEAD PPI (protein-protein interaction) inhibitor with IC50 is 2.7 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YAP-TEAD-IN-2 | 98.99% | YAP-TEAD-IN-2 (compound 6) is a potent YAP-TEAD PPI (protein-protein interaction) inhibitor with IC50 is 2.7 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-150256YTP-17 -
Similarity Score 0.67
HY-186022YAP/TAZ-TEAD-IN-3 -
Similarity Score 0.58
HY-186023TEAD ligand-Linker Conjugate 1 -
Similarity Score 0.53
HY-184179TEAD degrader-1 -
Similarity Score 0.53
HY-153811IAG933 -
Similarity Score 0.46
HY-186021PROTAC TEAD degrader-2 -
Similarity Score 0.46
HY-145361eIF4A3-IN-7 -
Similarity Score 0.46
HY-19356ADidesmethylrocaglamide -
Similarity Score 0.46
HY-148446eIF4A3-IN-12 -
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