2762762-17-2
2762762-17-2
Chemical Structure
LI-2242
- CAS 番号: 2762762-17-2
- Formula:C20H18Cl2N2O3
- Molecular Weight:405.27
IUPAC Name: 1'-(2,4-dichlorobenzyl)-2-oxospiro[indoline-3,4'-piperidine]-5-carboxylic acid
InChIKey: JHZGJEQBBFGROU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2NC(C3(CCN(CC3)CC4=CC=C(C=C4Cl)Cl)C2=C1)=O)O
Biological Activity:
LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor. LI-2242 has inhibition effect for IP6K1, IP6K2, IP6K3 and IPMK with IC50 values of 31 nM, 42 nM, 8.7 nM and 1944 nM, respectively. LI-2242 can be used for thew research of type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders[1].
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LI-2242 | 98.83% | LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor. LI-2242 has inhibition effect for IP6K1, IP6K2, IP6K3 and IPMK with IC50 values of 31 nM, 42 nM, 8.7 nM and 1944 nM, respectively. LI-2242 can be used for thew research of type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders. |
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