1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. DR4485 hydrochloride

DR4485 hydrochloride 

Cat. No.: HY-103126
Handling Instructions

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14).

For research use only. We do not sell to patients.

DR4485 hydrochloride Chemical Structure

DR4485 hydrochloride Chemical Structure

CAS No. : 402942-53-4

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DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14)[1].

IC50 & Target[1]

5-HT7 Receptor

8.14 (pKi)

In Vitro

DR4485 (MZ54 WT cells; 6 µM or 8 µM) hydrochloride induces autophagy as well as cell death that is diminished by KO of ATG5 and ATG7[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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