2768834-39-3
2768834-39-3
Chemical Structure
SARS-CoV-2 Mpro-IN-2
- CAS No.: 2768834-39-3
- Formula:C22H20Cl2N4O2S
- Molecular Weight:475.39
IUPAC Name: (S)-1-(3,4-dichlorophenyl)-4-nicotinoyl-N-(thiophen-2-ylmethyl)piperazine-2-carboxamide
InChIKey: XEFYJHCPILXFKJ-FQEVSTJZSA-N
SMILES: ClC(C=CC(N1CCN(C(C2=CN=CC=C2)=O)C[C@H]1C(NCC3=CC=CS3)=O)=C4)=C4Cl
Biological Activity: SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent Mpro inhibitor (IC50=0.40 μM) with good anti-SARS-CoV-2 activity (EC50=1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SARS-CoV-2 Mpro-IN-2 | 98.96% | SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent Mpro inhibitor (IC50=0.40 μM) with good anti-SARS-CoV-2 activity (EC50=1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.74
HY-152108SARS-CoV-2 Mpro-IN-6 -
Similarity Score 0.63
HY-149774GC-78-HCl -
Similarity Score 0.51
HY-149978LSD1-IN-26 -
Similarity Score 0.49
HY-163912JZD-07 -
Similarity Score 0.48
HY-115366Soluflazine -
Similarity Score 0.48
HY-111432CCG-232601 -
Similarity Score 0.47
HY-105542RNiaprazine (Standard) -
Similarity Score 0.47
HY-153161CASP8-IN-1 -
Similarity Score 0.47
HY-107660SIRT2-IN-8 -
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