2828431-89-4
2828431-89-4
Chemical Structure
A 83-01 sodium
- CAS No.: 2828431-89-4
- Formula:C25H19N5NaS
- Molecular Weight:444.51
IUPAC Name: 3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide, sodium salt
InChIKey: CLSYUDUYMVHOMO-UHFFFAOYSA-N
SMILES: S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5.[Na]
Biological Activity: A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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A 83-01 sodium | 98.03% | A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively. | ||||||||||||||||||||
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References
Keywords
