2851993-91-2
2851993-91-2
Chemical Structure
HHS-0701
- CAS No.: 2851993-91-2
- Formula:C20H20N4O3S
- Molecular Weight:396.46
IUPAC Name: (4-((1H-1,2,4-triazol-1-yl)sulfonyl)phenyl)(4-phenylpiperidin-1-yl)methanone
InChIKey: LLBIFOHOSLRVRY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(S(N2N=CN=C2)(=O)=O)C=C1)N3CCC(C4=CC=CC=C4)CC3
Biological Activity: HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2[1].
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HHS-0701 | HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. | |||||||||||||||||||||
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References
Keywords
