286008-51-3
286008-51-3
Chemical Structure
RDR03871
- CAS No.: 286008-51-3
- Formula:C18H16ClF3N6
- Molecular Weight:408.81
IUPAC Name: N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(6-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine
InChIKey: BDLJLGRTYOMPEG-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=CC(NCCNC2=NC(C3=NC=CC=C3)=NC(C)=C2Cl)=N1
Biological Activity: RDR03871 (compound 2) is a potent dual MDM2/MDM4 inhibitor with IC50 values of 35.4 nM and 10.4 nM for MDM2-p53 and MDM4-p53, respectively[1].
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RDR03871 | RDR03871 (compound 2) is a potent dual MDM2/MDM4 inhibitor with IC50 values of 35.4 nM and 10.4 nM for MDM2-p53 and MDM4-p53, respectively. | |||||||||||||||||||||
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References
Keywords
